A stereoselective anomaly in dicarboxylic amino acid transport.
نویسندگان
چکیده
منابع مشابه
Properties of a dicarboxylic amino acid transport-deficient mutant of Streptococcus faecalis.
A mutant of Sfrepfococcus faecalis has been isolated which has a ZO-fold higher growth requirement for L-glutamic acid than the parent strain. The ability to utilize L-glutamine for growth is not affected. The mutant also has a greater dependence than the parent strain on an external supply of vitamin B6. The rate of glutamic acid transport at low extracellular concentrations (0.05 mu) was grea...
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It has recently been shown that formation of podocyte foot processes is dependent on a constant source of lipids and proteins (Simons M, Saffrich R, Reiser J, and Mundel P. J Am Soc Nephrol 10: 1633-1639, 1999). Here we characterize amino acid transport mechanisms in differentiated cultured podocytes and investigate whether it may be disturbed during podocyte injury. RT-PCR studies detected mRN...
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Glutamate and aspartate influxes across the brush border of rabbit intestine are saturable processes that are subject to competitive inhibition and are markedly influenced by the Na concentration in the mucosal solution. Lowering the Na concentration increases the amino acid concentration needed to elicit a half-maximal influx but does not significantly affect the maximal influx. The interactio...
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I[I. Place of co-transport with Na ÷ . . . . . . . . . . . . . . . . . . . . . . . . . 489 A. Must the energy for Na+-dependent, uphill amino acid transport be channeled through alkali-metal gradients? . . . . . . . . . . . . . . . . . . . . . . . . . . . 489 B. Attempts to eliminate experimentally the alkali-metal ion gradients without dissipating other forms of transport-related energy storag...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1981
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)69127-1